Gene
prkar1b
- ID
- ZDB-GENE-060929-580
- Name
- protein kinase, cAMP-dependent, regulatory, type I, beta
- Symbol
- prkar1b Nomenclature History
- Previous Names
-
- zgc:153624
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cGMP-mediated signaling. Predicted to localize to cytosol. Orthologous to human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Marbach-Schaaf neurodevelopmental syndrome | 619680 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
Domain | IPR000595 | Cyclic nucleotide-binding domain |
Domain | IPR003117 | cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain |
Domain | IPR042818 | RIbeta, dimerization/docking domain |
Family | IPR012198 | cAMP-dependent protein kinase regulatory subunit |
Family | IPR050503 | cAMP-dependent kinase regulatory chain |
Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
Protein | Length | cAMP-dependent kinase regulatory chain | cAMP-dependent protein kinase regulatory subunit | cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | RIbeta, dimerization/docking domain | RmlC-like jelly roll fold |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q08C49
|
380 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
prkar1b-201
(1)
|
Ensembl | 1366 nt | |
mRNA |
prkar1b-202
(1)
|
Havana | 1428 nt | |
mRNA |
prkar1b-203
(1)
|
Ensembl | 1182 nt |
Interactions and Pathways
No data available
Plasmids
No data available