Gene
gbp4
- ID
- ZDB-GENE-060531-46
- Name
- guanylate binding protein 4
- Symbol
- gbp4 Nomenclature History
- Previous Names
-
- si:ch211-250m6.1 (1)
- si:dkey-61p9.3
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity and GTPase activity. Involved in neutrophil homeostasis and neutrophil mediated killing of bacterium. Predicted to localize to membrane. Orthologous to human GBP6 (guanylate binding protein family member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR003191 | Guanylate-binding protein/Atlastin, C-terminal |
| Domain | IPR015894 | Guanylate-binding protein, N-terminal |
| Domain | IPR030386 | GB1/RHD3-type guanine nucleotide-binding (G) domain |
| Domain | IPR033516 | CARD8/ASC/NALP1, CARD domain |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036543 | Guanylate-binding protein, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | Death-like domain superfamily | GB1/RHD3-type guanine nucleotide-binding (G) domain | Guanylate-binding protein/Atlastin, C-terminal | Guanylate-binding protein, C-terminal domain superfamily | Guanylate-binding protein, N-terminal | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5RJ11
|
618 | ||||||||
|
UniProtKB:Q1MT80
|
618 |
Interactions and Pathways
No data available
Plasmids
No data available