Gene
gbp4
- ID
- ZDB-GENE-060531-46
- Name
- guanylate binding protein 4
- Symbol
- gbp4 Nomenclature History
- Previous Names
-
- si:ch211-250m6.1 (1)
- si:dkey-61p9.3
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within neutrophil homeostasis and neutrophil-mediated killing of bacterium.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR003191 | Guanylate-binding protein/Atlastin, C-terminal |
| Domain | IPR015894 | Guanylate-binding protein, N-terminal |
| Domain | IPR030386 | GB1/RHD3-type guanine nucleotide-binding (G) domain |
| Domain | IPR033516 | CARD8/ASC/NALP1, CARD domain |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036543 | Guanylate-binding protein, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | Death-like domain superfamily | GB1/RHD3-type guanine nucleotide-binding (G) domain | Guanylate-binding protein/Atlastin, C-terminal | Guanylate-binding protein, C-terminal domain superfamily | Guanylate-binding protein, N-terminal | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5RJ11
|
618 | ||||||||
|
UniProtKB:Q1MT80
|
618 |
Interactions and Pathways
No data available
Plasmids
No data available