Gene

gbp4

ID
ZDB-GENE-060531-46
Name
guanylate binding protein 4
Symbol
gbp4 Nomenclature History
Previous Names
  • si:ch211-250m6.1 (1)
  • si:dkey-61p9.3
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have GTP binding activity and GTPase activity. Involved in neutrophil homeostasis and neutrophil-mediated killing of bacterium. Predicted to localize to cytoplasm. Orthologous to human GBP6 (guanylate binding protein family member 6).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gbp4 Human Ortholog
No data available
Associated With gbp4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001315 CARD domain
Domain IPR003191 Guanylate-binding protein/Atlastin, C-terminal
Domain IPR015894 Guanylate-binding protein, N-terminal
Domain IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
Domain IPR033516 CARD8/ASC/NALP1, CARD domain
Homologous_superfamily IPR011029 Death-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036543 Guanylate-binding protein, C-terminal domain superfamily
Domain Details Per Protein
Protein Length CARD8/ASC/NALP1, CARD domain CARD domain Death-like domain superfamily GB1/RHD3-type guanine nucleotide-binding (G) domain Guanylate-binding protein/Atlastin, C-terminal Guanylate-binding protein, C-terminal domain superfamily Guanylate-binding protein, N-terminal P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A4QNT4 618
UniProtKB:Q5RJ11 618
UniProtKB:Q1MT80 618
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-gbp4
  • WB
1
Ab2-gbp4
  • WB
1
Ab3-gbp4
  • WB
1
Ab4-gbp4
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations