Gene
amigo1
- ID
- ZDB-GENE-060503-114
- Name
- adhesion molecule with Ig-like domain 1
- Symbol
- amigo1 Nomenclature History
- Previous Names
-
- si:ch211-199o1.9 (1)
- si:ch211-77c7.1
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Involved in brain development. Predicted to localize to integral component of membrane. Is expressed in basal plate midbrain region and nervous system. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 11 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d0322 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Amphoterin-induced protein | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat N-terminal domain | Leucine-rich repeat, typical subtype |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M1QHZ7
|
491 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
amigo1-201
(1)
|
Ensembl | 1,366 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-amigo1 | Chicken |
|
1 |
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Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-77C7 | ZFIN Curated Data | |
Contained in | BAC | CH211-199O1 | ZFIN Curated Data | |
Encodes | EST | cssl:d0322 | Thisse et al., 2008 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_001923988 (1) | 6774 nt | ||
Genomic | GenBank:AL773601 | 201299 nt | ||
Polypeptide | UniProtKB:A0A8M1QHZ7 (1) | 491 aa |
- Román, A.C., Vicente-Page, J., Pérez-Escudero, A., Carvajal-González, J.M., Fernández-Salguero, P.M., de Polavieja, G.G. (2018) Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish. Genome biology. 19:55
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Panza, P., Sitko, A.A., Maischein, H.M., Koch, I., Flötenmeyer, M., Wright, G.J., Mandai, K., Mason, C.A., Söllner, C. (2015) The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm. Neural Development. 10:23
- Zhao, X., Kuja-Panula, J., Rouhiainen, A., Chen, Y.C., Panula, P., and Rauvala, H. (2011) High mobility group box-1 (HMGB1; amphoterin) is required for zebrafish brain development. The Journal of biological chemistry. 286(26):23200-13
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