ZFIN ID: ZDB-GENE-060503-114
Gene Name: adhesion molecule with Ig-like domain 1
Gene Symbol: amigo1    Nomenclature History

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Previous Names: si:ch211-199o1.9 (1), si:ch211-77c7.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Involved in brain development. Predicted to localize to the integral component of membrane. Is expressed in basal plate midbrain region and nervous system. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1).
Genome Resources: Alliance (1),  Gene:100144409 (1),  Ensembl(GRCz11):ENSDARG00000079620 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH amigo1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH amigo1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process brain development (more)
Cellular Component integral component of plasma membrane (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Family IPR031283 Amphoterin-induced protein
Family IPR031284 Amphoterin-induced protein 1
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA amigo1-201 (1)    Ensembl 1366
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-amigo1 Chicken IHC 1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM amigo1 No data available
MARKER RELATIONSHIPS
amigo1 Contained in: [BAC] CH211-77C7 (1), CH211-199O1 (1)
amigo1 Encodes: [EST] cssl:d0322 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_001923988 (1)
Genomic GenBank:AL773601 201299 nt Blast at MegaBLAST
Polypeptide UniProtKB:A8BAW4 (1) 368 aa
Sequence Information (all 10)
ORTHOLOGY for amigo1 ( Chr: 8 )
CITATIONS (19)