Gene

slco2b1

ID

ZDB-GENE-051023-6

Name

solute carrier organic anion transporter family, member 2B1

Symbol

slco2b1 Nomenclature History

Previous Names

Oatp2b1 (1)
im:7158298
wu:fi40d02
zgc:123236

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in bile acid and bile salt transport and sodium-independent organic anion transport. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including gill; liver; pleuroperitoneal region; skeletal muscle; and ventral mesenchyme. Orthologous to human SLCO2B1 (solute carrier organic anion transporter family member 2B1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158298 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Cacialli et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slco2b1 Human Ortholog

No data available

Associated With slco2b1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002350	Kazal domain
Family	IPR004156	Organic anion transporter polypeptide
Homologous_superfamily	IPR036058	Kazal domain superfamily
Homologous_superfamily	IPR036259	MFS transporter superfamily

Domain Details Per Protein

Protein	Length	Kazal domain	Kazal domain superfamily	MFS transporter superfamily	Organic anion transporter polypeptide
UniProtKB:F1Q5M5 InterPro	677

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slco2b1-201 (1) Ensembl	Ensembl	2,781 nt	Select Tool ZFIN BLAST
mRNA	slco2b1-204 (1) Ensembl	Ensembl	2,782 nt	Select Tool ZFIN BLAST
mRNA	slco2b1-206 (1) Ensembl	Ensembl	4,195 nt	Select Tool ZFIN BLAST
mRNA	slco2b1-207 (1) Ensembl	Ensembl	1,011 nt	Select Tool ZFIN BLAST
ncRNA	slco2b1-002 (1) Ensembl	Ensembl	1,029 nt	Select Tool ZFIN BLAST
ncRNA	slco2b1-003 (1) Ensembl	Ensembl	905 nt	Select Tool ZFIN BLAST
ncRNA	slco2b1-004 (1) Ensembl	Ensembl	899 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations