Gene
dhx8
- ID
- ZDB-GENE-050809-39
- Name
- DEAH (Asp-Glu-Ala-His) box polypeptide 8
- Symbol
- dhx8 Nomenclature History
- Previous Names
-
- im:7153552
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Involved in cell division; mRNA splicing, via endonucleolytic cleavage and ligation; and primitive hemopoiesis. Localizes to nucleus. Is expressed in brain; midbrain; and pronephric duct. Orthologous to human DHX8 (DEAH-box helicase 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153552 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from English et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002464 | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR003029 | S1 domain |
| Domain | IPR007502 | Helicase-associated domain |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR011709 | DEAD-box helicase, OB fold |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR044762 | DHX8/ Prp22, DEXH-box helicase domain |
| Domain | IPR048333 | Helicase associated domain (HA2), winged-helix domain |
| Domain | IPR049588 | DHX8, GH2-like domain |
| Domain | IPR049621 | DHX8 helicase, S1 domain |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | DEAD-box helicase, OB fold | DEAD/DEAH box helicase domain | DHX8, GH2-like domain | DHX8 helicase, S1 domain | DHX8/ Prp22, DEXH-box helicase domain | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site | Helicase-associated domain | Helicase associated domain (HA2), winged-helix domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | Nucleic acid-binding, OB-fold | P-loop containing nucleoside triphosphate hydrolase | S1 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q925
|
1210 |
Interactions and Pathways
No data available
Plasmids
No data available