Gene

pip5k1aa

ID

ZDB-GENE-050522-517

Name

phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a

Symbol

pip5k1aa Nomenclature History

Previous Names

pip5k1a
zgc:110576

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and ATP binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol metabolic process and phosphorylation. Predicted to be active in plasma membrane. Is expressed in head and pronephric duct. Orthologous to human PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7159737 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Xu et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pip5k1aa Human Ortholog

No data available

Associated With pip5k1aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002498	Phosphatidylinositol-4-phosphate 4/5-kinase, core
Family	IPR023610	Phosphatidylinositol-4/5-phosphate 5/4-kinase
Homologous_superfamily	IPR027483	Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Homologous_superfamily	IPR027484	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal