Gene

katna1

ID
ZDB-GENE-050522-514
Name
katanin p60 (ATPase containing) subunit A 1
Symbol
katna1 Nomenclature History
Previous Names
  • si:dkey-15j16.1
  • zgc:110580 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have microtubule-severing ATPase activity. Involved in axon extension and cytoplasmic microtubule organization. Predicted to localize to several cellular components, including midbody; mitotic spindle pole; and nucleus. Orthologous to human KATNA1 (katanin catalytic subunit A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Butler et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With katna1 Human Ortholog
No data available
Associated With katna1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR015415 Spastin/Vps4, C-terminal
Domain IPR041569 AAA ATPase, AAA+ lid domain
Domain IPR048611 Katanin p60 ATPase-containing subunit A1, MIT domain
Domain IPR048612 Katanin p60 ATPase-containing subunit A1, AAA domain
Family IPR028596 Katanin p60 subunit A1
Family IPR050304 Microtubule-severing AAA ATPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA ATPase, AAA+ lid domain AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core Katanin p60 ATPase-containing subunit A1, AAA domain Katanin p60 ATPase-containing subunit A1, MIT domain Katanin p60 subunit A1 Microtubule-severing AAA ATPase P-loop containing nucleoside triphosphate hydrolase Spastin/Vps4, C-terminal
UniProtKB:A0A8M9PHA7 485
UniProtKB:Q5RII9 485
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA katna1-201 (1) Ensembl 2,355 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-katna1 polyclonal Mouse
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations