ZFIN is now using GRCz12tu for Genomic Data
Gene
rab23
- ID
- ZDB-GENE-050522-328
- Name
- RAB23, member RAS oncogene family
- Symbol
- rab23 Nomenclature History
- Previous Names
-
- zgc:110261
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTPase activity. Acts upstream of or within determination of left/right symmetry. Predicted to be located in phagocytic vesicle membrane and plasma membrane. Predicted to be active in autophagosome and endosome membrane. Human ortholog(s) of this gene implicated in Carpenter syndrome 1. Orthologous to human RAB23 (RAB23, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110261 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Carpenter syndrome 1 | Alliance | Carpenter syndrome | 201000 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Carpenter syndrome 1 | AB + MO3-rab23 | control | Leong et al., 2025 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rab | Ras-related protein Rab-23 | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q503R5 | InterPro | 237 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers