Gene
stmn2b
- ID
- ZDB-GENE-050522-207
- Name
- stathmin 2b
- Symbol
- stmn2b Nomenclature History
- Previous Names
-
- stmn2
- SCG10a (1)
- zgc:110132
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable tubulin binding activity. Acts upstream of or within nervous system development. Predicted to be active in cytoplasm and growth cone. Is expressed in several structures, including basal plate midbrain region; nervous system; pronephric duct; spinal cord neural tube; and trigeminal placode. Orthologous to human STMN2 (stathmin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110132 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la020760Tg | Transgenic insertion | Unknown | Unknown | DNA |
1 - 1 of 1
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-stmn2b | N/A | Alves et al., 2010 |
| MO2-stmn2b | N/A | Carretero-Rodriguez et al., 2021 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Stathmin family | Stathmin superfamily |
|---|---|---|---|---|
| UniProtKB:Q4VBT7 | InterPro | 180 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stmn2b-201
(1)
|
Ensembl | 1,822 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-120H9 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:110132 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001024222 (1) | 1484 nt | ||
| Genomic | GenBank:BX322551 (1) | 152069 nt | ||
| Polypeptide | UniProtKB:Q4VBT7 (1) | 180 aa |
- Jing, Y., Luo, Y., Li, L., Liu, M., Liu, J.X. (2024) Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell biology and toxicology. 40:22
- Zhu, H., Zhang, X., Xu, S., Wu, J., Hou, M., Zhao, H., Zhou, Q., Zhong, X. (2022) Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. Journal of experimental zoology. Part B, Molecular and developmental evolution. 338(5):301-313
- Carretero-Rodriguez, L., Guðjónsdóttir, R., Poparic, I., Reilly, M.L., Chol, M., Bianco, I.H., Chiapello, M., Feret, R., Deery, M.J., Guthrie, S. (2021) The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(31):6652-6672
- Wang, M., Du, L., Lee, A.C., Li, Y., Qin, H., He, J. (2020) Different lineage contexts direct common pro-neural factors to specify distinct retinal cell subtypes. The Journal of cell biology. 219(9):
- Zuccarini, G., D'Atri, I., Cottone, E., Mackie, K., Shainer, I., Gothilf, Y., Provero, P., Bovolin, P., Merlo, G.R. (2019) Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos. International Journal of Molecular Sciences. 21(1):
- Cardoso, J.C., Bergqvist, C.A., Felix, R.C., Larhammar, D. (2016) Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages. Journal of molecular endocrinology. 57(1):73-86
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Baraban, M., Anselme, I., Schneider-Maunoury, S., and Giudicelli, F. (2013) Zebrafish embryonic neurons transport messenger RNA to axons and growth cones in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(40):15726-15734
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Veerkamp, J., Rudolph, F., Cseresnyes, Z., Priller, F., Otten, C., Renz, M., Schaefer, L., and Abdelilah-Seyfried, S. (2013) Unilateral dampening of bmp activity by nodal generates cardiac left-right asymmetry. Developmental Cell. 24(6):660-667
1 - 10 of 15
Show