Gene

abcd4

ID

ZDB-GENE-050517-30

Name

ATP-binding cassette, sub-family D (ALD), member 4

Symbol

abcd4 Nomenclature History

Previous Names

zgc:153503

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; ATPase activity; and ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane. Orthologous to human ABCD4 (ATP binding cassette subfamily D member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Choi et al., 2019

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Choi et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcd4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Methylmalonic aciduria and homocystinuria, cblJ type	614857

Associated With abcd4 Via Experimental Models

Human Disease	Fish	Conditions	Citations
vitamin B12 deficiency	abcd4^wk1/wk1	standard conditions	Choi et al., 2019
vitamin B12 deficiency	WT + MO1-abcd4	standard conditions	Choi et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR050835	ATP-binding cassette sub-family D
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily