Gene

uggt2

ID

ZDB-GENE-050517-21

Name

UDP-glucose glycoprotein glucosyltransferase 2

Symbol

uggt2 Nomenclature History

Previous Names

ugcgl2
im:7146988
wu:fi13a08

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ER-associated misfolded protein catabolic process and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With uggt2 Human Ortholog

No data available

Associated With uggt2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040497	Glucosyltransferase 24, catalytic domain
Domain	IPR040525	UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4
Domain	IPR040692	UGGT, thioredoxin-like domain 3
Domain	IPR040693	UGGT, thioredoxin-like domain 1
Domain	IPR040694	UGGT, thioredoxin-like domain 2
Family	IPR009448	UDP-glucose:Glycoprotein Glucosyltransferase
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases

Domain Details Per Protein

Protein	Length	Glucosyltransferase 24, catalytic domain	Nucleotide-diphospho-sugar transferases	UDP-glucose:Glycoprotein Glucosyltransferase	UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4	UGGT, thioredoxin-like domain 1	UGGT, thioredoxin-like domain 2	UGGT, thioredoxin-like domain 3
UniProtKB:A0A8M3AW54 InterPro	1528
UniProtKB:A0A8M3AW47 InterPro	1520
UniProtKB:E7F6G9 InterPro	1527

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	uggt2-201 (1) Ensembl	Ensembl	5,379 nt	Select Tool ZFIN BLAST
mRNA	uggt2-203 (1) Ensembl	Ensembl	4,569 nt	Select Tool ZFIN BLAST
mRNA	uggt2-204 (1) Ensembl	Ensembl	4,593 nt	Select Tool ZFIN BLAST
ncRNA	uggt2-002 (1) Ensembl	Ensembl	751 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations