Gene

ndufs3

ID

ZDB-GENE-050417-274

Name

NADH:ubiquinone oxidoreductase core subunit S3

Symbol

ndufs3 Nomenclature History

Previous Names

zgc:112520

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in male organism. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 8. Orthologous to human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7148616 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndufs3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 8	Alliance	Mitochondrial complex I deficiency, nuclear type 8	618230

Associated With ndufs3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020396	NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
Domain	IPR001268	NADH:ubiquinone oxidoreductase, 30kDa subunit
Family	IPR010218	NADH dehydrogenase, subunit C
Homologous_superfamily	IPR037232	NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily