Gene

sertad3

ID

ZDB-GENE-050327-34

Name

SERTA domain containing 3

Symbol

sertad3 Nomenclature History

Previous Names

zgc:113340

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable transcription coactivator activity. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including SERTAD3 (SERTA domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:113340 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With sertad3 Human Ortholog

No data available

Associated With sertad3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009263	SERTA domain
Family	IPR052262	E2F-responsive SERTA domain-containing protein

Domain Details Per Protein

Protein	Additional Resources	Length	E2F-responsive SERTA domain-containing protein	SERTA domain
UniProtKB:B8JMC2	InterPro	244

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 18

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	zgc:113340-201 (1) Ensembl	Ensembl		1,746 nt	Select Tool ZFIN BLAST
mRNA	zgc:113340-202 (1) Ensembl	Ensembl		3,690 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH73-262H23	CU595952	ZFIN Curated Data
Encodes	cDNA	MGC:113340	BC091808	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001014321 (1)	1063 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU595952 (1)	82981 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:B8JMC2 (1)	244 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	SERTAD1	19	Ensembl:ENSG00000197019 Gene:29950 HGNC:17932 OMIM:617850	Conserved genome location (synteny) (1)
Human	SERTAD3	19	Ensembl:ENSG00000167565 Gene:29946 HGNC:17931 OMIM:612125	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Sertad1	7	Ensembl:ENSMUSG00000008384 Gene:55942 MGI:1913438	Conserved genome location (synteny) (1)
Mouse	Sertad3	7	Ensembl:ENSMUSG00000055200 Gene:170742 MGI:2180697	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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