Gene

hibch

ID

ZDB-GENE-050327-29

Name

3-hydroxyisobutyryl-CoA hydrolase

Symbol

hibch Nomenclature History

Previous Names

zgc:110824

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have 3-hydroxyisobutyryl-CoA hydrolase activity. Predicted to be involved in valine catabolic process. Predicted to localize to mitochondrion. Orthologous to human HIBCH (3-hydroxyisobutyryl-CoA hydrolase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110824 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hibch Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
3-hydroxyisobutryl-CoA hydrolase deficiency	Alliance	3-hydroxyisobutryl-CoA hydrolase deficiency	250620

Associated With hibch Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR045004	Enoyl-CoA hydratase/isomerase domain
Family	IPR032259	Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type
Homologous_superfamily	IPR029045	ClpP/crotonase-like domain superfamily