Gene
phf2
- ID
- ZDB-GENE-050302-10
- Name
- PHD finger protein 2
- Symbol
- phf2 Nomenclature History
- Previous Names
-
- phf8
- im:4200679
- wu:fa14c10
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have several functions, including histone demethylase activity (H3-K9 specific); transcription coactivator activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of chromatin silencing at rDNA. Predicted to localize to kinetochore and nucleolus. Orthologous to human PHF2 (PHD finger protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR041070 | Jumonji, helical domain |
| Family | IPR050690 | JHDM1 Histone Demethylase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | JHDM1 Histone Demethylase | JmjC domain | Jumonji, helical domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P949
|
1063 | ||||||||
|
UniProtKB:A0A8M2BH62
|
1059 | ||||||||
|
UniProtKB:A0A8M2BGL0
|
1066 |
Interactions and Pathways
No data available
Plasmids
No data available