Gene
stab1
- ID
- ZDB-GENE-050208-554
- Name
- stabilin 1
- Symbol
- stab1 Nomenclature History
- Previous Names
-
- stab1l
- si:dkeyp-87e7.6
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Enables scavenger receptor activity. Acts upstream of or within several processes, including cholesterol homeostasis; low-density lipoprotein particle clearance; and oxidised low-density lipoprotein particle clearance. Predicted to be located in membrane. Is expressed in several structures, including axis; caudal hematopoietic tissue; pharynx; post-vent region; and vasculature. Orthologous to human STAB1 (stabilin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu453 (5 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Hyperferritinemia] | 620729 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000538 | Link domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR000782 | FAS1 domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR024731 | EGF domain |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR036378 | FAS1 domain superfamily |
Domain Details Per Protein
| Protein | Length | C-type lectin fold | C-type lectin-like/link domain superfamily | EGF domain | EGF-like calcium-binding domain | EGF-like domain | FAS1 domain | FAS1 domain superfamily | Laminin-type EGF domain | Link domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E0CZJ3
|
2553 |
Interactions and Pathways
No data available
Plasmids
No data available