Gene

prkcq

ID
ZDB-GENE-041210-195
Name
protein kinase C, theta
Symbol
prkcq Nomenclature History
Previous Names
  • si:ch211-239o15.1
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Located in immunological synapse. Is expressed in Mauthner neurons; brain; somite border; and spinal cord. Orthologous to human PRKCQ (protein kinase C theta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Patten et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa2170Allele with one point mutationUnknownSplice SiteENU
sa20289Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With prkcq Human Ortholog
No data available
Associated With prkcq Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
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Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C1-like domain superfamily C2 domain superfamily Diacylglycerol/phorbol-ester binding Novel protein kinase C theta, catalytic domain Protein kinase, ATP binding site Protein kinase C, delta/epsilon/eta/theta types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinases, AGC
UniProtKB:A0A8M3B909 719
UniProtKB:F1R506 713
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prkcq-201 (1) Ensembl 2,142 nt
mRNA prkcq-202 (1) Ensembl 2,128 nt
mRNA prkcq-203 (1) Ensembl 1,173 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prkcq polyclonal IgG Rabbit
  • IHC
  • WB
Santa Cruz Biotechnology, Inc.
1
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-239O15ZFIN Curated Data
EncodescDNAMGC:162992ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPRKCQ10
Conserved genome location (synteny) (2)
Nucleotide sequence comparison (1)
Phylogenetic tree (2)
Amino acid sequence comparison (2)
MousePrkcq2
Amino acid sequence comparison (2)
Nucleotide sequence comparison (1)
Conserved genome location (synteny) (2)
Phylogenetic tree (2)
Citations
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