ZFIN ID: ZDB-GENE-041210-195
Gene Name: protein kinase C, theta
Gene Symbol: prkcq    Nomenclature History

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Previous Name: si:ch211-239o15.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Localizes to immunological synapse. Is expressed in Mauthner neurons; brain; somite border; and spinal cord. Orthologous to human PRKCQ (protein kinase C theta).
Genome Resources: Alliance (1),  Gene:555521 (1),  Ensembl(GRCz11):ENSDARG00000034173 (2)
GENE EXPRESSION
All Expression Data: 3 figures from Patten et al., 2007
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2170 Point Mutation Unknown Splice Site ENU
sa20289 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prkcq HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prkcq VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Cellular Component immunological synapse (more)
    Molecular Function ATP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prkcq-202 (1)    Ensembl 2128
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-prkcq polyclonal IgG Rabbit IHC, WB Santa Cruz Biotechnology, Inc.
    1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prkcq No data available
    MARKER RELATIONSHIPS
    prkcq Contained in: [BAC] CH211-239O15 (1)
    prkcq Encodes: [cDNA] MGC:162992 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089370 (1) 1299 nt
    Genomic GenBank:AL954652 (1) 152900 nt
    Select Tool
    Polypeptide UniProtKB:F1R506 (1) 713 aa
    Sequence Information (all 18)
    ORTHOLOGY for prkcq ( Chr: 4 )
    CITATIONS (25)