Gene
shroom4
- ID
- ZDB-GENE-041111-246
- Name
- shroom family member 4
- Symbol
- shroom4 Nomenclature History
- Previous Names
-
- im:7145757
- wu:fe05h01
- zgc:194172
- zgc:194173
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to localize to several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to human SHROOM4 (shroom family member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145757 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Kolvenbach et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apx/Shrm Domain 2 | PDZ domain | PDZ superfamily | Shroom family |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7TES2
|
1508 | ||||
|
UniProtKB:F1Q6C1
|
1634 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
shroom4-201
(1)
|
Ensembl | 6,362 nt | ||
| mRNA |
shroom4-202
(1)
|
Ensembl | 541 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-shroom4 | polyclonal | Rabbit |
|
2 |
Plasmids
No data available