Gene
atf6
- ID
- ZDB-GENE-041014-328
- Name
- activating transcription factor 6
- Symbol
- atf6 Nomenclature History
- Previous Names
-
- fi12h10
- si:ch211-199m3.9
- si:ch211-260g14.1
- wu:fi12h10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in nucleus. Is expressed in head; liver; nervous system; and trunk. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 53 figures from 40 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cinaroglu et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 7 | Alliance | Achromatopsia 7 | 616517 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ATF bZIP Transcription Factors | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily |
|---|---|---|---|---|
|
UniProtKB:Q5RH85
|
653 |
Interactions and Pathways
No data available
Plasmids