Gene
nitr9
- ID
- ZDB-GENE-041001-6
- Name
- novel immune-type receptor 9
- Symbol
- nitr9 Nomenclature History
- Previous Names
-
- nitr9.1 (1)
- zgc:123078
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in phosphatidylinositol 3-kinase signaling and response to bacterium. Predicted to localize to integral component of membrane. Is expressed in digestive system; gill; immune system; and myeloid cell.
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003599 | Immunoglobulin domain subtype |
Domain | IPR007110 | Immunoglobulin-like domain |
Family | IPR052051 | T cell receptor complex component |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
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Domain Details Per Protein
Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | T cell receptor complex component |
---|---|---|---|---|---|---|
UniProtKB:Q5YCY6
|
285 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-46N24 | ZFIN Curated Data | |
Contained in | BAC | CH73-266M14 | ZFIN Curated Data | |
Contained in | BAC | CH211-262G18 | ZFIN Curated Data | |
Contained in | BAC | DKEY-7N10 | ZFIN Curated Data | |
Encodes | EST | cssl:d0615 | Thisse et al., 2008 | |
Encodes | EST | cssl:d0616 | Thisse et al., 2008 | |
Encodes | cDNA | MGC:123078 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001425101 (1) | 1125 nt | ||
Genomic | GenBank:CR931785 (1) | 196531 nt | ||
Polypeptide | UniProtKB:Q5YCY6 (1) | 285 aa |
No data available
- Muire, P.J., Hanson, L.A., Wills, R., Petrie-Hanson, L. (2017) Differential gene expression following TLR stimulation in rag1-/- mutant zebrafish tissues and morphological descriptions of lymphocyte-like cell populations. PLoS One. 12:e0184077
- Shah, R.N., Rodriguez-Nunez, I., Eason, D.D., Haire, R.N., Bertrand, J.Y., Wittamer, V., Traver, D., Nordone, S.K., Litman, G.W., and Yoder, J.A. (2012) Development and characterization of anti-nitr9 antibodies. Advances in hematology. 2012:596925
- Yoder, J.A., Turner, P.M., Wright, P.D., Wittamer, V., Bertrand, J.Y., Traver, D., and Litman, G.W. (2010) Developmental and tissue-specific expression of NITRs. Immunogenetics. 62(2):117-122
- Rojo, I., de Ilárduya, O.M., Estonba, A., and Pardo, M.A. (2007) Innate immune gene expression in individual zebrafish after Listonella anguillarum inoculation. Fish & shellfish immunology. 23(6):1285-1293
- Wei, S., Zhou, J.M., Chen, X., Shah, R.N., Liu, J., Orcutt, T.M., Traver, D., Djeu, J.Y., Litman, G.W., and Yoder, J.A. (2007) The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 59(10):813-821
- Yoder, J.A., Litman, R.T., Mueller, M.G., Desai, S., Dobrinski, K.P., Montgomery, J.S., Buzzeo, M.P., Ota, T., Amemiya, C.T., Trede, N.S., Wei, S., Djeu, J.Y., Humphray, S., Jekosch, K., Hernandez Prada, J.A., Ostrov, D.A., and Litman, G.W. (2004) Resolution of the novel immune-type receptor gene cluster in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101(44):15706-15711
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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