Gene
lmod2a
- ID
- ZDB-GENE-040912-41
- Name
- leiomodin 2 (cardiac) a
- Symbol
- lmod2a Nomenclature History
- Previous Names
-
- zgc:103424
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and tropomyosin binding activity. Predicted to be involved in muscle contraction and myofibril assembly. Predicted to act upstream of or within pointed-end actin filament capping. Predicted to be active in striated muscle thin filament. Is expressed in atrium. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G. Orthologous to human LMOD2 (leiomodin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103424 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 2G | Alliance | Cardiomyopathy, dilated, 2G | 619897 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat domain superfamily | Tropomodulin | WH2 domain |
|---|---|---|---|---|
|
UniProtKB:A0A2R8RJX3
|
461 | |||
|
UniProtKB:Q66I90
|
263 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lmod2a-201
(1)
|
Ensembl | 1,058 nt |
Interactions and Pathways
No data available
Plasmids
No data available