Gene
alg6
- ID
- ZDB-GENE-040808-45
- Name
- ALG6 alpha-1,3-glucosyltransferase
- Symbol
- alg6 Nomenclature History
- Previous Names
-
- zgc:100813 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6901735 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Ic | Alliance | Congenital disorder of glycosylation, type Ic | 603147 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004856 | Glycosyl transferase, ALG6/ALG8 |
Domain Details Per Protein
| Protein | Length | Glycosyl transferase, ALG6/ALG8 |
|---|---|---|
|
UniProtKB:A0A8M3B3H3
|
295 | |
|
UniProtKB:A0A8M1N1I1
|
506 | |
|
UniProtKB:Q6AXK8
|
227 |
Interactions and Pathways
No data available
Plasmids
No data available