Gene

mmp24

ID

ZDB-GENE-040724-262

Name

matrix metallopeptidase 24

Symbol

mmp24 Nomenclature History

Previous Names

si:ch211-239j9.5

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular matrix and plasma membrane. Orthologous to human MMP24 (matrix metallopeptidase 24).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Quick et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mmp24 Human Ortholog

No data available

Associated With mmp24 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018486	Hemopexin, conserved site
Domain	IPR000585	Hemopexin-like domain
Domain	IPR001818	Peptidase M10, metallopeptidase
Domain	IPR002477	Peptidoglycan binding-like
Domain	IPR006026	Peptidase, metallopeptidase
Domain	IPR021805	Peptidase M10A, matrix metallopeptidase, C-terminal
Domain	IPR033739	Peptidase M10A, catalytic domain
Family	IPR021190	Peptidase M10A
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036365	PGBD-like superfamily
Homologous_superfamily	IPR036375	Hemopexin-like domain superfamily
Repeat	IPR018487	Hemopexin-like repeats

Domain Details Per Protein

Protein	Length	Hemopexin, conserved site	Hemopexin-like domain	Hemopexin-like domain superfamily	Hemopexin-like repeats	Metallopeptidase, catalytic domain superfamily	Peptidase M10A	Peptidase M10A, catalytic domain	Peptidase M10A, matrix metallopeptidase, C-terminal	Peptidase M10, metallopeptidase	Peptidase, metallopeptidase	Peptidoglycan binding-like	PGBD-like superfamily
UniProtKB:E9QIX9 InterPro	606

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	mmp24-201 (1) Ensembl	Ensembl		4,126 nt	Select Tool ZFIN BLAST
mRNA	mmp24-202 (1) Ensembl	Ensembl		1,623 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations