Gene
plaat1
- ID
- ZDB-GENE-040718-330
- Name
- phospholipase A and acyltransferase 1
- Symbol
- plaat1 Nomenclature History
- Previous Names
-
- hrasls
- zgc:92715 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to localize to integral component of membrane. Orthologous to human PLAAT1 (phospholipase A and acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92715 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Morishita et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | H-rev107 Phospholipase/Acyltransferase | LRAT domain |
---|---|---|---|
UniProtKB:A0A8D3IFC9
|
|||
UniProtKB:A0A0R4IY06
|
179 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
hrasls-201
(1)
|
Ensembl | 825 nt | ||
mRNA |
plaat1-202
(1)
|
Ensembl | 1,166 nt |
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Interactions and Pathways
No data available
Plasmids
Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
---|---|---|---|---|---|
Tg(cryaa:EGFP-plaat1) |
|
| 1 | Morishita et al., 2021 |
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Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Encodes | cDNA | MGC:92715 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001002590 (1) | 837 nt | ||
Genomic | GenBank:FQ323135 (1) | 13389 nt | ||
Polypeptide | UniProtKB:A0A0R4IY06 (1) | 179 aa |
- Zhao, X., Huang, W., Guo, J., Ji, N., Feng, J., Shi, Y., Chen, K., Zou, J. (2022) PLAAT1 promotes p53 degradation via autophagy-lysosome pathway in zebrafish. Fish & shellfish immunology. 125:48-53
- Zhao, X., Huang, W., Shi, Y., Guo, J., Xiao, H., Ji, N., Feng, J., Dang, H., Zou, J. (2022) PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish. Frontiers in immunology. 13:979919
- Morishita, H., Eguchi, T., Tsukamoto, S., Sakamaki, Y., Takahashi, S., Saito, C., Koyama-Honda, I., Mizushima, N. (2021) Organelle degradation in the lens by PLAAT phospholipases. Nature. 592(7855):634-638
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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