Gene

tpm4a

ID
ZDB-GENE-040426-2185
Name
tropomyosin 4a
Symbol
tpm4a Nomenclature History
Previous Names
  • TPM4-1 (1)
  • tpm4
  • wu:fb06e07
  • zgc:103436
  • zgc:63909
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Involved in cardiac muscle contraction and cardiac myofibril assembly. Predicted to localize to actin filament. Is expressed in several structures, including cardiovascular system; head mesenchyme; mesoderm; muscle; and thymus. Orthologous to human TPM4 (tropomyosin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpm4a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Bleeding disorder, platelet-type, 25 620486
Associated With tpm4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000533 Tropomyosin
Homologous_superfamily IPR014751 DNA repair protein XRCC4-like, C-terminal
Domain Details Per Protein
Protein Length DNA repair protein XRCC4-like, C-terminal Tropomyosin
UniProtKB:Q7T3F0 248
UniProtKB:F1R412 284
UniProtKB:Q5U3J6 284
UniProtKB:A0A8M6Z3C6 248
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tpm4a-201 (1) Ensembl 1,119 nt
mRNA tpm4a-202 (1) Ensembl 2,384 nt
mRNA tpm4a-203 (1) Ensembl 2,842 nt
mRNA tpm4a-204 (1) Ensembl 743 nt
mRNA tpm4a-205 (1) Ensembl 1,261 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations