Gene
spint1a
- ID
- ZDB-GENE-040426-2169
- Name
- serine peptidase inhibitor, Kunitz type 1 a
- Symbol
- spint1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Involved in several processes, including collagen fibril organization; epidermis development; and neutrophil chemotaxis. Predicted to localize to integral component of membrane. Is expressed in several structures, including apical ectodermal ridge; digestive system; fin fold pectoral fin bud; periderm; and sensory system. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb376 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 42 figures from 13 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
Conserved_site | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
Domain | IPR011106 | Seven cysteines, N-terminal |
Domain | IPR013980 | MANSC domain |
Domain | IPR022409 | PKD/Chitinase domain |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR035986 | PKD domain superfamily |
Homologous_superfamily | IPR036055 | LDL receptor-like superfamily |
Homologous_superfamily | IPR036880 | Pancreatic trypsin inhibitor Kunitz domain superfamily |
Repeat | IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat |
Domain Details Per Protein
Protein | Length | Immunoglobulin-like fold | LDL receptor-like superfamily | Low-density lipoprotein (LDL) receptor class A, conserved site | Low-density lipoprotein (LDL) receptor class A repeat | MANSC domain | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | PKD/Chitinase domain | PKD domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Seven cysteines, N-terminal |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A2R8QCE4
|
523 | |||||||||||
UniProtKB:Q7T363
|
516 | |||||||||||
UniProtKB:A0A8M9P036
|
506 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available