Gene
timm50
- ID
- ZDB-GENE-040426-1618
- Name
- translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
- Symbol
- timm50 Nomenclature History
- Previous Names
-
- zgc:66357 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Involved in apoptotic process. Predicted to localize to TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Is expressed in several structures, including immature eye; margin; midbrain; pectoral fin musculature; and segmental plate. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66357 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3-methylglutaconic aciduria type 9 | Alliance | 3-methylglutaconic aciduria, type IX | 617698 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FCP1 homology domain | HAD-like superfamily | HAD superfamily | Mitochondrial import inner membrane translocase subunit TIM50 |
|---|---|---|---|---|---|
|
UniProtKB:Q6NWD4
|
387 | ||||
|
UniProtKB:B2GQE9
|
387 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timm50-201
(1)
|
Ensembl | 1,807 nt |
Interactions and Pathways
No data available
Plasmids
No data available