Gene

dhx38

ID

ZDB-GENE-040426-1144

Name

DEAH (Asp-Glu-Ala-His) box polypeptide 38

Symbol

dhx38 Nomenclature History

Previous Names

zgc:63517 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to localize to spliceosomal complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human DHX38 (DEAH-box helicase 38).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63517 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dhx38 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 84	Alliance	Retinitis pigmentosa 84	618220

Associated With dhx38 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002464	DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR007502	Helicase-associated domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR011709	DEAD-box helicase, OB fold
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR048333	Helicase associated domain (HA2), winged-helix domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase