Gene
tlr7
- ID
- ZDB-GENE-040219-11
- Name
- toll-like receptor 7
- Symbol
- tlr7 Nomenclature History
- Previous Names
-
- TLR7A (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have single-stranded RNA binding activity and transmembrane signaling receptor activity. Predicted to be involved in defense response to other organism and toll-like receptor signaling pathway. Predicted to localize to cytoskeleton and integral component of membrane. Is expressed in several structures, including blood; heart; integument; liver; and pleuroperitoneal region. Orthologous to human TLR7 (toll like receptor 7).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
X-Linked immunodeficiency 74 | Alliance | Immunodeficiency 74, COVID19-related, X-linked | 301051 |
Systemic lupus erythematosus 17 | 301080 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain |
Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Homologous_superfamily | IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
Repeat | IPR001611 | Leucine-rich repeat |
Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
Protein | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | Toll/interleukin-1 receptor homology (TIR) domain | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QKF3
|
1036 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available