Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040213-2
Gene Name: cytochrome P450, family 17, subfamily A, polypeptide 1
Gene Symbol: cyp17a1
Previous Names: cyp17 (1), P450c17 (1), wu:fi13g04, wu:fi17b11, wu:fi31c08, zgc:136516, zgc:66494
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7157435]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, Leydig cell, ovarian follicle, ovarian follicle stage I (all 11) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa22316
Knockdown reagents: MO1-cyp17a1 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
17,20-lyase deficiency, isolated 202110
17-alpha-hydroxylase/17,20-lyase deficiency 202110
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Molecular Function heme binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp17a1-001 (1) 2799
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-cyp17a1 (1)
    CONSTRUCTS WITH SEQUENCES FROM cyp17a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp17a1 Contained in: [BAC] CH211-67N3 (1) (order this)
    cyp17a1 Contains: [SNP] rs3728563 (1), rs3728564 (1), rs3728565 (1)
    cyp17a1 Encodes: [EST] fi13g04, fi17b11, fi31c08, IMAGE:7157435 (1) (order this)
    [cDNA] MGC:66494 (1) (order this), MGC:136516 (1) (order this), MGC:194068 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212806 (1) 2799 bp
    Genomic GenBank:AL928951 (1) 183050 bp
    Select Tool
    Polypeptide UniProtKB:A2ATX9 (1) 519 aa
    Sequence Clusters UniGene:79318 (1)
    Sequence Information (all 37)
    OTHER cyp17a1 GENE PAGES
  • Gene:399692 (1)
  • VEGA:OTTDARG00000018827 (1)
  • Ensembl(Zv9):ENSDARG00000033566 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cyp17a1 13  
    Human CYP17A1 10 (10q24.3)
  • OMIM:609300
  • Gene:1586
  • Mouse Cyp17a1 19 ( 38.97 cM)
  • MGI:88586
  • Gene:13074
  • Orthology Details
    CITATIONS (48)