ZFIN ID: ZDB-GENE-040213-2
Gene Name: cytochrome P450, family 17, subfamily A, polypeptide 1
Gene Symbol: cyp17a1
Sequence Ontology ID : SO:0000704

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Previous Names: cyp17 (1), P450c17 (1), wu:fi13g04, wu:fi17b11, wu:fi31c08, zgc:136516, zgc:66494

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7157435]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, Leydig cell, ovarian follicle, ovarian follicle stage I (all 11) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb144 Small Deletion Unknown Unknown TALEN
sa7373 Point Mutation Unknown Nonsynonymous ENU
sa22316 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa35505 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-cyp17a1 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp17a1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital adrenal hyperplasia 17,20-lyase deficiency, isolated 202110
    17-alpha-hydroxylase/17,20-lyase deficiency 202110
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process androst-4-ene-3,17-dione biosynthetic process (more)
    Molecular Function 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • InterPro:IPR033282 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp17a1-001 (1) 2799
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-cyp17a1 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyp17a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp17a1Contained in: [BAC] CH211-67N3 (1) (order this)
    cyp17a1Contains: [SNP] rs3728563 (1), rs3728564 (1), rs3728565 (1)
    cyp17a1Encodes: [EST] fi13g04, fi17b11, fi31c08, IMAGE:7157435 (1) (order this)
    [cDNA] MGC:66494 (1) (order this), MGC:136516 (1) (order this), MGC:194068 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212806 (1) 2799bp
    Genomic GenBank:AL928951 (1) 183050bp
    Select Tool
    Polypeptide UniProtKB:A2ATX9 (1) 519aa
    Sequence Clusters UniGene:109966 (1)
    Sequence Information (all 37)
    OTHER cyp17a1 GENE PAGES
  • Gene:399692 (1)
  • VEGA:OTTDARG00000018827 (1)
  • Ensembl(GRCz10):ENSDARG00000033566 (1)
  • ORTHOLOGY for cyp17a1 (Chr: 13)
    CITATIONS (85)