Gene
ntf3
- ID
- ZDB-GENE-031118-66
- Name
- neurotrophin 3
- Symbol
- ntf3 Nomenclature History
- Previous Names
-
- NT-3 (1)
- ntf3-pen
- wu:fl98d04
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity. Involved in negative regulation of programmed cell death and peripheral nervous system development. Predicted to localize to several cellular components, including axon; dendrite; and synaptic vesicle. Human ortholog(s) of this gene implicated in Alzheimer's disease and asthma. Is expressed in several structures, including brain; cardiovascular system; otic placode; pancreas primordium; and retina. Orthologous to human NTF3 (neurotrophin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | Nerve growth factor conserved site | Nerve growth factor-like | Nerve growth factor-related | Neurotrophin-3 | Neutrophin-3, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1P3S4
|
256 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ntf3 | polyclonal | IgG | Rabbit |
|
Thermo Fisher Scientific (Lab Vision)
|
2 |
Plasmids
No data available