| ZFIN ID: ZDB-GENE-031118-121 |
| Gene Name: | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog |
|---|---|
| Gene Symbol: | erbb2 |
| Previous Names: | wu:fv70f10, zgc:63601 |
| Nomenclature History | |
| All Expression Data: | 3 figures from 3 publications |
| Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth) |
|---|---|
cranial ganglion,
fin,
lens,
melanocyte
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| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 12 genotypes |
| Alleles: |
la012096Tg,
la012097Tg,
la012098Tg,
la018007Tg,
st50
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| Knockdown reagents: | MO1-erbb2 (1), MO2-erbb2 (1) |
| Data: | 5 figures from 3 publications |
| Observed in: |
dorsal root ganglion neuron,
fin regeneration,
posterior lateral line nerve axon,
posterior lateral line nerve myelin sheath
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| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Adenocarcinoma of lung, somatic | 211980 |
| Gastric cancer, somatic | 613659 |
| Glioblastoma, somatic | 137800 |
| Ovarian cancer, somatic, |
| Ontology | GO Term |
|---|---|
| Biological Process | Schwann cell development (more) |
| Cellular Component | integral to membrane (more) |
| Molecular Function | ATP binding (more) |
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| Type | Name | Length (bp) | Analysis | |
|---|---|---|---|---|
| mRNA | erbb2-001 (1) | 4093 |
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| ncRNA | erbb2-002 (1) | 765 |
Select Tool
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| erbb2 Contained in: | [BAC] DKEY-25P11 (1) (order this) |
| erbb2 Has Artifact: |
[EST]
fv70f10
[cDNA] WITHDRAWN:MGC:63601 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_200119 (1) | 3956 bp |
Select Tool
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| Genomic | GenBank:CR457459 (1) | 206901 bp | Blast at MegaBLAST |
| Polypeptide | UniProtKB:Q5EBY4 (1) | 1275 aa |
Select Tool
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| Sequence Clusters | UniGene:52559 (1) |
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| Chr: 12 Details |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | erbb2 | 12 |
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| Human | ERBB2 | 17 (17q12) |
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