Gene

ackr3b

ID
ZDB-GENE-031116-61
Name
atypical chemokine receptor 3b
Symbol
ackr3b Nomenclature History
Previous Names
  • CXCR7 (1)
  • cxcr7b (1)
  • drRDC1b (1)
  • sb:cb900
  • si:dkey-96h14.2
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Exhibits chemokine binding activity. Involved in several processes, including blood vessel morphogenesis; nervous system development; and posterior lateral line neuromast primordium migration. Predicted to localize to external side of plasma membrane. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; immature eye; nervous system; and neural rod. Orthologous to human ACKR3 (atypical chemokine receptor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
48 figures from 31 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ackr3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Oculomotor-abducens synkinesis 619215
Associated With ackr3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001416 Atypical chemokine receptor 3
Family IPR047143 G-protein coupled estrogen receptor 1-like
Domain Details Per Protein
Protein Length Atypical chemokine receptor 3 GPCR, rhodopsin-like, 7TM G-protein coupled estrogen receptor 1-like G protein-coupled receptor, rhodopsin-like
UniProtKB:A4IG54 362
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ackr3b-201 (1) Ensembl 1,953 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ackr3b monoclonal Mouse
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations