Gene
parp2
- ID
- ZDB-GENE-031113-6
- Name
- poly (ADP-ribose) polymerase 2
- Symbol
- parp2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Predicted to be involved in double-strand break repair and protein poly-ADP-ribosylation. Predicted to localize to nucleolus. Is expressed in brain; head; and proliferative region. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb996 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain |
| Domain | IPR004170 | WWE domain |
| Domain | IPR008893 | WGR domain |
| Domain | IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain |
| Domain | IPR018123 | WWE domain, subgroup |
| Family | IPR050800 | ADP-ribosyltransferase diphtheria toxin-like |
| Homologous_superfamily | IPR036616 | Poly(ADP-ribose) polymerase, regulatory domain superfamily |
| Homologous_superfamily | IPR036930 | WGR domain superfamily |
| Homologous_superfamily | IPR037197 | WWE domain superfamily |
Domain Details Per Protein
| Protein | Length | ADP-ribosyltransferase diphtheria toxin-like | Poly(ADP-ribose) polymerase, catalytic domain | Poly(ADP-ribose) polymerase, regulatory domain | Poly(ADP-ribose) polymerase, regulatory domain superfamily | WGR domain | WGR domain superfamily | WWE domain | WWE domain, subgroup | WWE domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QAF7
|
648 | |||||||||
|
UniProtKB:A0A8M9QIR2
|
649 |
Interactions and Pathways
No data available
Plasmids
No data available