Gene

parp2

ID
ZDB-GENE-031113-6
Name
poly (ADP-ribose) polymerase 2
Symbol
parp2 Nomenclature History
Previous Names
  • adprtl2 (1)
  • cb996 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Predicted to be involved in double-strand break repair and protein poly-ADP-ribosylation. Predicted to localize to nucleolus. Is expressed in brain; head; and proliferative region. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With parp2 Human Ortholog
No data available
Associated With parp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004102 Poly(ADP-ribose) polymerase, regulatory domain
Domain IPR004170 WWE domain
Domain IPR008893 WGR domain
Domain IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
Domain IPR018123 WWE domain, subgroup
Family IPR050800 ADP-ribosyltransferase diphtheria toxin-like
Homologous_superfamily IPR036616 Poly(ADP-ribose) polymerase, regulatory domain superfamily
Homologous_superfamily IPR036930 WGR domain superfamily
Homologous_superfamily IPR037197 WWE domain superfamily
Domain Details Per Protein
Protein Length ADP-ribosyltransferase diphtheria toxin-like Poly(ADP-ribose) polymerase, catalytic domain Poly(ADP-ribose) polymerase, regulatory domain Poly(ADP-ribose) polymerase, regulatory domain superfamily WGR domain WGR domain superfamily WWE domain WWE domain, subgroup WWE domain superfamily
UniProtKB:F1QAF7 648
UniProtKB:A0A8M9QIR2 649
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA parp2-201 (1) Ensembl 2,198 nt
mRNA parp2-202 (1) Ensembl 813 nt
mRNA parp2-203 (1) Ensembl 2,629 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations