Gene

tead3a

ID

ZDB-GENE-031112-10

Name

TEA domain family member 3 a

Symbol

tead3a Nomenclature History

Previous Names

tead3
cb882 (1)
si:ch211-194j14.2

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within Kupffer's vesicle development; cilium assembly; and determination of heart left/right asymmetry. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including central nervous system; head; musculature system; pericardial region; and segmental plate. Orthologous to human TEAD3 (TEA domain transcription factor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb882 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Fillatre et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tead3a Human Ortholog

No data available

Associated With tead3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000818	TEA/ATTS domain
Domain	IPR041086	YAP binding domain
Family	IPR016361	Transcriptional enhancer factor, metazoa
Family	IPR027253	Transcriptional enhancer factor TEF-5 (TEAD3)
Family	IPR050937	TEC1/TEAD Transcription Factor
Homologous_superfamily	IPR038096	TEA/ATTS domain superfamily

Domain Details Per Protein

Protein	Length	TEA/ATTS domain	TEA/ATTS domain superfamily	TEC1/TEAD Transcription Factor	Transcriptional enhancer factor, metazoa	Transcriptional enhancer factor TEF-5 (TEAD3)	YAP binding domain
UniProtKB:A0A8M9PWP5 InterPro	473
UniProtKB:F1Q968 InterPro	405
UniProtKB:A0A8M9PF88 InterPro	477
UniProtKB:A0A8M9PTB3 InterPro	473
UniProtKB:A0A2R8QCP0 InterPro	409
UniProtKB:A0A8M9PKY0 InterPro	477

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tead3a-201 (1) Ensembl	Ensembl	1,330 nt	Select Tool ZFIN BLAST
mRNA	tead3a-202 (1) Ensembl	Ensembl	492 nt	Select Tool ZFIN BLAST
mRNA	tead3a-203 (1) Ensembl	Ensembl	1,342 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations