Gene

trpv1

ID

ZDB-GENE-030912-8

Name

transient receptor potential cation channel, subfamily V, member 1

Symbol

trpv1 Nomenclature History

Previous Names

TRPV1/2 (1)
si:dkey-9e15.2

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have calcium channel activity. Involved in response to heat and thermosensory behavior. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in colorectal cancer; congenital stationary night blindness; focal nonepidermolytic palmoplantar keratoderma 2; migraine (multiple); and schizophrenia. Is expressed in several structures, including epithelium; heart; keratinocyte; nervous system; and pleuroperitoneal region. Orthologous to several human genes including TRPV1 (transient receptor potential cation channel subfamily V member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 9 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Chen et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trpv1 Human Ortholog

No data available

Associated With trpv1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005821	Ion transport domain
Family	IPR008347	Transient receptor potential cation channel subfamily V member 1-4
Family	IPR024862	Transient receptor potential cation channel subfamily V
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	Ion transport domain	Transient receptor potential cation channel subfamily V	Transient receptor potential cation channel subfamily V member 1-4
UniProtKB:B6RTA2 InterPro	819
UniProtKB:B0S711 InterPro	813

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trpv1-201 (1) Ensembl	Ensembl	3,046 nt	Select Tool ZFIN BLAST
mRNA	trpv1-202 (1) Ensembl	Ensembl	2,442 nt	Select Tool ZFIN BLAST
mRNA	trpv1-203 (1) Ensembl	Ensembl	2,464 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-trpv1	polyclonal	trpv1	IgG	Rabbit	IHC WB	Thermo Fisher Scientific (Lab Vision)	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations