Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030909-9
Gene Name: glutamate decarboxylase 2
Gene Symbol: gad2
Previous Names: gad65 (1), GAD65 (1), zgc:112198
Location: Chr: 24   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 11 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  cerebellum, corpus cerebelli Purkinje cell, Golgi cell, granular layer corpus cerebelli (all 14) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la023079Tg, la023080Tg
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process gamma-aminobutyric acid biosynthetic process (more)
Cellular Component cellular_component (more)
Molecular Function carboxy-lyase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • InterPro:IPR021115 (1)
  • PROSITE:PS00392 (1)
  • Pfam:PF00282 (1)
  • EC:4.1.1.15 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gad2-001 (1) 6409
    ncRNA gad2-002 (1) 511
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-gad2 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gad2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gad2 Contained in: [BAC] CH211-37E10 (1) (order this), DKEY-48C13 (1)
    gad2 Encodes: [cDNA] MGC:112198 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017708 (1) 6411 bp
    Genomic GenBank:BX530066 (1) 202859 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R9E8 (1) 583 aa
    Sequence Clusters UniGene:81033 (1)
    Sequence Information (all 14)
    OTHER gad2 GENE PAGES
  • Gene:550403 (1)
  • VEGA:OTTDARG00000021333 (1)
  • Ensembl(Zv9):ENSDARG00000015537 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish gad2 24  
    Human GAD2 10 (10p11.23)
  • OMIM:138275
  • Gene:2572
  • Mouse Gad2 2 ( 15.15 cM)
  • MGI:95634
  • Gene:14417
  • Orthology Details
    CITATIONS (41)