ZFIN ID: ZDB-GENE-030909-9
Gene Name: glutamate decarboxylase 2
Gene Symbol: gad2
Previous Names: GAD65 (1), gad65 (1), zgc:112198
Location: Chr: 24 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 27 figures from 12 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  cerebellum, corpus cerebelli Purkinje cell, forebrain, Golgi cell (all 21) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la023079Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023080Tg Transgenic Insertion DNA
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gad2 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gamma-aminobutyric acid biosynthetic process (more)
    Cellular Component cellular_component (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • InterPro:IPR021115 (1)
  • PROSITE:PS00392 (1)
  • Pfam:PF00282 (1)
  • EC:4.1.1.15 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gad2-001 (1) 6409
    ncRNA gad2-002 (1) 511
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-gad2 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gad2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gad2Contained in: [BAC] CH211-37E10 (1) (order this), DKEY-48C13 (1) (order this)
    gad2Encodes: [cDNA] MGC:112198 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017708 (1) 6411bp
    Genomic GenBank:BX530066 (1) 202859bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R9E8 (1) 583aa
    Sequence Clusters UniGene:81033 (1)
    Sequence Information (all 14)
    OTHER gad2 GENE PAGES
  • Gene:550403 (1)
  • VEGA:OTTDARG00000021333 (1)
  • Ensembl(GRCz10):ENSDARG00000015537 (1)
  • ORTHOLOGY for gad2 (Chr: 24)
    Species Symbol Chromosome Accession # Evidence
    Human GAD2 10
  • Gene:2572
  • OMIM:138275
  • HGNC:4093
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Gad2 2
  • MGI:95634
  • Gene:14417
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (43)