ZFIN ID: ZDB-GENE-030909-9
Gene Name: glutamate decarboxylase 2
Gene Symbol: gad2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: GAD65 (1), gad65 (1), zgc:112198

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have glutamate decarboxylase activity and pyridoxal phosphate binding activity; involved in gamma-aminobutyric acid biosynthetic process; orthologous to human GAD2 (glutamate  ...
GENE EXPRESSION
All Expression Data: 35 figures from 20 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023079Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023080Tg Transgenic Insertion Unknown Unknown DNA
    sa30034 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37819 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gad2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gad2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gamma-aminobutyric acid biosynthetic process (more)
    Cellular Component cellular_component (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015424 (1)
  • InterPro:IPR021115 (1)
  • PROSITE:PS00392 (1)
  • Pfam:PF00282 (1)
  • EC:4.1.1.15 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA gad2-002 (1) 511
    mRNA gad2-201 (1) 6409
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gad2 No data available
    MARKER RELATIONSHIPS
    gad2Contained in: [BAC] CH211-37E10 (1) (order this), DKEY-48C13 (1) (order this)
    gad2Encodes: [cDNA] MGC:112198 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017708 (1) 6411bp
    Genomic GenBank:BX530066 (1) 202859bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R9E8 (1) 583aa
    Sequence Clusters UniGene:81033 (1)
    Sequence Information (all 17)
    OTHER gad2 GENE PAGES
  • Alliance (1)
  • Gene:550403 (1)
  • VEGA:OTTDARG00000021333 (1)
  • Ensembl(GRCz11):ENSDARG00000015537 (2)
  • ORTHOLOGY for gad2 (Chr: 24)
    CITATIONS (68)