Gene

prmt5

ID
ZDB-GENE-030616-585
Name
protein arginine methyltransferase 5
Symbol
prmt5 Nomenclature History
Previous Names
  • PRMT5 (1)
  • si:zc14a17.2
  • skb1 (1)
  • wu:fb95f10
  • zgc:110669
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have histone-arginine N-methyltransferase activity. Involved in regulation of skeletal muscle fiber development. Predicted to localize to cytosol and nucleus. Is expressed in segmental plate; shield; and somite. Orthologous to human PRMT5 (protein arginine methyltransferase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prmt5 Human Ortholog
No data available
Associated With prmt5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR035075 PRMT5 arginine-N-methyltransferase
Domain IPR035247 PRMT5, TIM barrel domain
Domain IPR035248 PRMT5, oligomerisation domain
Family IPR007857 Protein arginine N-methyltransferase PRMT5
Family IPR025799 Protein arginine N-methyltransferase
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Domain Details Per Protein
Protein Length PRMT5 arginine-N-methyltransferase PRMT5, oligomerisation domain PRMT5, TIM barrel domain Protein arginine N-methyltransferase Protein arginine N-methyltransferase PRMT5 S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:Q503E3 631
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prmt5-201 (1) Ensembl 2,459 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
AB2-prmt5 monoclonal Rabbit
  • IHC
  • WB
1
Ab1-prmt5 polyclonal IgG Rabbit
  • IHC
  • WB
Millipore
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations