Gene

kdm7aa

ID
ZDB-GENE-030131-9829
Name
lysine (K)-specific demethylase 7Aa
Symbol
kdm7aa Nomenclature History
Previous Names
  • kdm7a (1)
  • cb414 (1)
  • jhdm1da
  • sb:cb414
  • si:dkey-105o6.2
  • zgc:123306
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Exhibits histone demethylase activity (H3-K27 specific) and histone demethylase activity (H3-K9 specific). Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and midbrain development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in melanoma. Is expressed in several structures, including anterior axial hypoblast; immature eye; margin; mesoderm; and nervous system. Orthologous to human KDM7A (lysine demethylase 7A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm7aa Human Ortholog
No data available
Associated With kdm7aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Domain IPR001965 Zinc finger, PHD-type
Domain IPR003347 JmjC domain
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR041070 Jumonji, helical domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Domain Details Per Protein
Protein Length JmjC domain Jumonji, helical domain Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site
UniProtKB:A0A2R8RKB3 837
UniProtKB:Q5RHD1 875
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations