Gene

mbd3b

ID

ZDB-GENE-030131-9792

Name

methyl-CpG binding domain protein 3b

Symbol

mbd3b Nomenclature History

Previous Names

cb357 (1)
cb99 (1)
sb:cb357
sb:cb99
wu:fc41c05
zgc:111851

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have methyl-CpG binding activity. Involved in definitive hemopoiesis and hematopoietic progenitor cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including Kupffer's vesicle; central nervous system; forerunner cell group; midbrain neural keel; and retina. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb99 (8 images)
cb357 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mbd3b Human Ortholog

No data available

Associated With mbd3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001739	Methyl-CpG DNA binding
Domain	IPR025884	Methyl-CpG binding protein 2/3, C-terminal domain
Domain	IPR032343	Methyl-CpG-binding domain protein 2/3, p55-binding region
Homologous_superfamily	IPR016177	DNA-binding domain superfamily