Gene
adkb
- ID
- ZDB-GENE-030131-948
- Name
- adenosine kinase b
- Symbol
- adkb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have adenosine kinase activity. Predicted to be involved in phosphorylation and purine ribonucleoside salvage. Predicted to localize to cytosol and nucleus. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Is expressed in several structures, including alar plate midbrain region; liver; midbrain; musculature system; and segmental plate. Orthologous to human ADK (adenosine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb980 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypermethioninemia due to adenosine kinase deficiency | Alliance | Hypermethioninemia due to adenosine kinase deficiency | 614300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adenosine kinase | Carbohydrate kinase PfkB | Carbohydrate/purine kinase, PfkB, conserved site | Ribokinase-like |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZTT5
|
345 |
Interactions and Pathways
No data available
Plasmids
No data available