Gene
kdm4ab
- ID
- ZDB-GENE-030131-6279
- Name
- lysine (K)-specific demethylase 4A, genome duplicate b
- Symbol
- kdm4ab Nomenclature History
- Previous Names
-
- jmjd2A (1)
- jmjd2al
- si:ch211-262l3.1
- wu:fi42b08
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Involved in blood vessel morphogenesis. Predicted to localize to histone methyltransferase complex. Human ortholog(s) of this gene implicated in several diseases, including autistic disorder; esophagus squamous cell carcinoma; head and neck cancer; renal cell carcinoma; and withdrawal disorder. Orthologous to several human genes including KDM4A (lysine demethylase 4A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR002999 | Tudor domain |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR003349 | JmjN domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR034732 | Extended PHD (ePHD) domain |
| Domain | IPR040477 | Lysine-specific demethylase 4-like, Tudor domain |
| Domain | IPR047481 | Lysine-specific demethylase 4A, second Tudor domain |
| Domain | IPR047482 | Lysine-specific demethylase 4A, extended PHD finger |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | Extended PHD (ePHD) domain | JmjC domain | JmjN domain | Lysine-specific demethylase 4A, extended PHD finger | Lysine-specific demethylase 4A, second Tudor domain | Lysine-specific demethylase 4-like, Tudor domain | Tudor domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QNG0
|
1045 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kdm4ab-201
(1)
|
Ensembl | 4,339 nt | ||
| mRNA |
kdm4ab-202
(1)
|
Ensembl | 3,490 nt |
Interactions and Pathways
No data available
Plasmids
No data available