Gene
iqgap2
- ID
- ZDB-GENE-030131-2878
- Name
- IQ motif containing GTPase activating protein 2
- Symbol
- iqgap2 Nomenclature History
- Previous Names
-
- fc20f09
- si:ch211-157p10.1
- wu:fc20f09
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Involved in glomerular filtration and glomerular visceral epithelial cell development. Is expressed in several structures, including cranial vasculature; gut; pericardial region; pronephros; and sensory system. Orthologous to human IQGAP2 (IQ motif containing GTPase activating protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR000048 | IQ motif, EF-hand binding site |
Domain | IPR000593 | RasGAP protein, C-terminal |
Domain | IPR001202 | WW domain |
Domain | IPR001715 | Calponin homology domain |
Domain | IPR001936 | Ras GTPase-activating domain |
Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
Protein | Length | Calponin homology domain | CH domain superfamily | IQ motif, EF-hand binding site | P-loop containing nucleoside triphosphate hydrolase | RasGAP protein, C-terminal | Ras GTPase-activating domain | Rho GTPase activation protein | WW domain |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A2CE93
|
1680 | ||||||||
UniProtKB:F1QAC1
|
1673 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
iqgap2-201
(1)
|
Ensembl | 9187 nt | |
mRNA |
iqgap2-202
(1)
|
Havana | 5192 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-iqgap2 | polyclonal | Rabbit |
|
EUROGENTEC S.A.
|
1 |
Plasmids
No data available