Gene
ell2
- ID
- ZDB-GENE-030131-1717
- Name
- elongation factor for RNA polymerase II 2
- Symbol
- ell2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II and snRNA transcription by RNA polymerase II. Predicted to act upstream of or within transcription elongation by RNA polymerase II and translational elongation. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including anterior axial hypoblast; hatching gland; mesoderm; musculature system; and sensory system. Orthologous to human ELL2 (elongation factor for RNA polymerase II 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb244 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010844 | Occludin homology domain |
| Domain | IPR019464 | RNA polymerase II elongation factor ELL, N-terminal |
| Family | IPR031176 | ELL/occludin family |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR042065 | E3 ubiquitin-protein ligase ELL-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase ELL-like | ELL/occludin family | Occludin homology domain | RNA polymerase II elongation factor ELL, N-terminal | Winged helix DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PI38 | InterPro | 338 | |||||
| UniProtKB:Q5U3C7 | InterPro | 626 | |||||
| UniProtKB:F1R2K7 | InterPro | 655 |
Interactions and Pathways
No data available
Plasmids
No data available