ZFIN ID: ZDB-GENE-030116-2
Gene Name: estrogen receptor 2a
Gene Symbol: esr2a
Previous Names: ER[b]2 (1), ER[b]a (1), ERbeta-B (1), NR3A2-B (1), zfER[b]2 (1)
Location: Chr: 20   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 23 figures from 13 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2008 [bc044349]
  1 figure (1 image) from Thisse et al., 2005 [eu81]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adipose tissue, blastoderm, blastodisc, blastomere (all 24) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-esr2a (1), MO2-esr2a (1), MO3-esr2a (1), MO4-esr2a (1)

Allele Type Mutagen Suppliers
la021455Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16405 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 7 figures from 2 publications
    Observed in: apoptotic process, basibranchial, brain, brain development (all 25) expand
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to estrogen (more)
    Cellular Component nucleus (more)
    Molecular Function estrogen receptor activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR008946 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR021064 (1)
  • InterPro:IPR024178 (1)
  • InterPro:IPR028355 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  • Pfam:PF12497 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA esr2a-001 (1) 3249
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM esr2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    esr2a Contained in: [BAC] DKEY-274C14 (1) (order this)
    esr2a Encodes: [EST] bc044349 (1) (order this), eu81 (1), fi14h07
    [cDNA] MGC:55251 (1) (order this), MGC:192492 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_180966 (1) 3111 bp
    Genomic GenBank:BX255911 (1) 206480 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q7ZU32 (1) 553 aa
    Sequence Clusters UniGene:80416 (1)
    Sequence Information (all 38)
    OTHER esr2a GENE PAGES
  • Gene:317734 (1)
  • VEGA:OTTDARG00000004945 (1)
  • Ensembl(Zv9):ENSDARG00000016454 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT
    Zebrafish esr2a 20  
    Human ESR2 14 (14q23.2)
  • OMIM:601663
  • Gene:2100
  • Mouse Esr2 12 ( 33.52 cM)
  • MGI:109392
  • Gene:13983
  • Orthology Details
    CITATIONS (66)